Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks.
Identifieur interne : 000647 ( Main/Exploration ); précédent : 000646; suivant : 000648Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks.
Auteurs : Hossam M. Ashour [États-Unis] ; Walid F. Elkhatib [Égypte] ; Md Masudur Rahman [Bangladesh] ; Hatem A. Elshabrawy [États-Unis]Source :
- Pathogens (Basel, Switzerland) [ 2076-0817 ] ; 2020.
Abstract
Coronaviruses (CoVs) are RNA viruses that have become a major public health concern since the Severe Acute Respiratory Syndrome-CoV (SARS-CoV) outbreak in 2002. The continuous evolution of coronaviruses was further highlighted with the emergence of the Middle East Respiratory Syndrome-CoV (MERS-CoV) outbreak in 2012. Currently, the world is concerned about the 2019 novel CoV (SARS-CoV-2) that was initially identified in the city of Wuhan, China in December 2019. Patients presented with severe viral pneumonia and respiratory illness. The number of cases has been mounting since then. As of late February 2020, tens of thousands of cases and several thousand deaths have been reported in China alone, in addition to thousands of cases in other countries. Although the fatality rate of SARS-CoV-2 is currently lower than SARS-CoV, the virus seems to be highly contagious based on the number of infected cases to date. In this review, we discuss structure, genome organization, entry of CoVs into target cells, and provide insights into past and present outbreaks. The future of human CoV outbreaks will not only depend on how the viruses will evolve, but will also depend on how we develop efficient prevention and treatment strategies to deal with this continuous threat.
DOI: 10.3390/pathogens9030186
PubMed: 32143502
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000763
- to stream PubMed, to step Curation: 000763
- to stream PubMed, to step Checkpoint: 000602
- to stream Ncbi, to step Merge: 000E18
- to stream Ncbi, to step Curation: 000E18
- to stream Ncbi, to step Checkpoint: 000E18
- to stream Main, to step Merge: 000649
- to stream Main, to step Curation: 000647
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks.</title><author><name sortKey="Ashour, Hossam M" sort="Ashour, Hossam M" uniqKey="Ashour H" first="Hossam M" last="Ashour">Hossam M. Ashour</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biological Sciences, College of Arts and Sciences, University of South Florida St. Petersburg, St. Petersburg, FL 33701, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Sciences, College of Arts and Sciences, University of South Florida St. Petersburg, St. Petersburg, FL 33701</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Elkhatib, Walid F" sort="Elkhatib, Walid F" uniqKey="Elkhatib W" first="Walid F" last="Elkhatib">Walid F. Elkhatib</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, School of Pharmacy & Pharmaceutical Industries, Badr University in Cairo (BUC), Entertainment Area, Badr City, Cairo 11829, Egypt.</nlm:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Department of Microbiology and Immunology, School of Pharmacy & Pharmaceutical Industries, Badr University in Cairo (BUC), Entertainment Area, Badr City, Cairo 11829</wicri:regionArea><wicri:noRegion>Cairo 11829</wicri:noRegion></affiliation></author><author><name sortKey="Rahman, Md Masudur" sort="Rahman, Md Masudur" uniqKey="Rahman M" first="Md Masudur" last="Rahman">Md Masudur Rahman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100, Bangladesh.</nlm:affiliation><country xml:lang="fr">Bangladesh</country><wicri:regionArea>Department of Pathology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100</wicri:regionArea><wicri:noRegion>Sylhet 3100</wicri:noRegion></affiliation></author><author><name sortKey="Elshabrawy, Hatem A" sort="Elshabrawy, Hatem A" uniqKey="Elshabrawy H" first="Hatem A" last="Elshabrawy">Hatem A. Elshabrawy</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32143502</idno><idno type="pmid">32143502</idno><idno type="doi">10.3390/pathogens9030186</idno><idno type="wicri:Area/PubMed/Corpus">000763</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000763</idno><idno type="wicri:Area/PubMed/Curation">000763</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000763</idno><idno type="wicri:Area/PubMed/Checkpoint">000602</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000602</idno><idno type="wicri:Area/Ncbi/Merge">000E18</idno><idno type="wicri:Area/Ncbi/Curation">000E18</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E18</idno><idno type="wicri:doubleKey">2076-0817:2020:Ashour H:insights:into:the</idno><idno type="wicri:Area/Main/Merge">000649</idno><idno type="wicri:Area/Main/Curation">000647</idno><idno type="wicri:Area/Main/Exploration">000647</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks.</title><author><name sortKey="Ashour, Hossam M" sort="Ashour, Hossam M" uniqKey="Ashour H" first="Hossam M" last="Ashour">Hossam M. Ashour</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biological Sciences, College of Arts and Sciences, University of South Florida St. Petersburg, St. Petersburg, FL 33701, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Sciences, College of Arts and Sciences, University of South Florida St. Petersburg, St. Petersburg, FL 33701</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Elkhatib, Walid F" sort="Elkhatib, Walid F" uniqKey="Elkhatib W" first="Walid F" last="Elkhatib">Walid F. Elkhatib</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, School of Pharmacy & Pharmaceutical Industries, Badr University in Cairo (BUC), Entertainment Area, Badr City, Cairo 11829, Egypt.</nlm:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Department of Microbiology and Immunology, School of Pharmacy & Pharmaceutical Industries, Badr University in Cairo (BUC), Entertainment Area, Badr City, Cairo 11829</wicri:regionArea><wicri:noRegion>Cairo 11829</wicri:noRegion></affiliation></author><author><name sortKey="Rahman, Md Masudur" sort="Rahman, Md Masudur" uniqKey="Rahman M" first="Md Masudur" last="Rahman">Md Masudur Rahman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100, Bangladesh.</nlm:affiliation><country xml:lang="fr">Bangladesh</country><wicri:regionArea>Department of Pathology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100</wicri:regionArea><wicri:noRegion>Sylhet 3100</wicri:noRegion></affiliation></author><author><name sortKey="Elshabrawy, Hatem A" sort="Elshabrawy, Hatem A" uniqKey="Elshabrawy H" first="Hatem A" last="Elshabrawy">Hatem A. Elshabrawy</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></analytic><series><title level="j">Pathogens (Basel, Switzerland)</title><idno type="ISSN">2076-0817</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Coronaviruses (CoVs) are RNA viruses that have become a major public health concern since the Severe Acute Respiratory Syndrome-CoV (SARS-CoV) outbreak in 2002. The continuous evolution of coronaviruses was further highlighted with the emergence of the Middle East Respiratory Syndrome-CoV (MERS-CoV) outbreak in 2012. Currently, the world is concerned about the 2019 novel CoV (SARS-CoV-2) that was initially identified in the city of Wuhan, China in December 2019. Patients presented with severe viral pneumonia and respiratory illness. The number of cases has been mounting since then. As of late February 2020, tens of thousands of cases and several thousand deaths have been reported in China alone, in addition to thousands of cases in other countries. Although the fatality rate of SARS-CoV-2 is currently lower than SARS-CoV, the virus seems to be highly contagious based on the number of infected cases to date. In this review, we discuss structure, genome organization, entry of CoVs into target cells, and provide insights into past and present outbreaks. The future of human CoV outbreaks will not only depend on how the viruses will evolve, but will also depend on how we develop efficient prevention and treatment strategies to deal with this continuous threat.</div></front></TEI><affiliations><list><country><li>Bangladesh</li><li>Égypte</li><li>États-Unis</li></country><region><li>Floride</li><li>Texas</li></region></list><tree><country name="États-Unis"><region name="Floride"><name sortKey="Ashour, Hossam M" sort="Ashour, Hossam M" uniqKey="Ashour H" first="Hossam M" last="Ashour">Hossam M. Ashour</name></region><name sortKey="Elshabrawy, Hatem A" sort="Elshabrawy, Hatem A" uniqKey="Elshabrawy H" first="Hatem A" last="Elshabrawy">Hatem A. Elshabrawy</name></country><country name="Égypte"><noRegion><name sortKey="Elkhatib, Walid F" sort="Elkhatib, Walid F" uniqKey="Elkhatib W" first="Walid F" last="Elkhatib">Walid F. Elkhatib</name></noRegion></country><country name="Bangladesh"><noRegion><name sortKey="Rahman, Md Masudur" sort="Rahman, Md Masudur" uniqKey="Rahman M" first="Md Masudur" last="Rahman">Md Masudur Rahman</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000647 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000647 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32143502
|texte= Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32143502" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |